Table 1 Preoperative characteristics.

From: Tranexamic acid in primary total knee arthroplasty without tourniquet: a randomized, controlled trial of oral versus intravenous versus topical administration

Variable

Oral TXA Group (N = 60)

IV TXA Group (N = 60)

IA TXA Group (N = 60)

P value

Demographic characteristics

  Age (yr)

63.91 ± 13.07

66.90 ± 9.48

63.20 ± 11.75

0.19

  Male sex (no. [%])

18 (30%)

15 (25%)

16 (27%)

0.82

  Height (cm)

1.58 ± 0.69

1.57 ± 0.67

1.57 ± 0.57

0.61

  Weight (kg)

63.21 ± 11.17

61.87 ± 9.34

63.05 ± 9.75

0.73

  BMI (kg/m2)

25.27 ± 4.17

25.04 ± 3.41

25.53 ± 3.81

0.77

  Operated side, left/right (no. [%])

39 (65%)

34 (57%)

37 (62%)

0.64

ASA classification (no. of patients)

  I

7 (12%)

8 (13%)

7 (12%)

0.97

  II

39 (65%)

40 (67%)

41 (68%)

 

  III

14 (23%)

12 (20%)

11 (18%)

 

  IV

0 (0%)

0 (0%)

0 (0%)

 

  Caprini score (point)

8.2 ± 0.95

8.33 ± 1.09

8.46 ± 1.19

0.41

Preop. values (blood routine)

  Hemoglobin (g/dL)

13.40 ± 1.40

13.35 ± 1.17

13.37 ± 1.23

0.98

  Hematocrit (L/L)

0.41 ± 0.04

0.41 ± 0.03

0.40 ± 0.03

0.09

  Platelet count (×109/L)

185.28 ± 54.68

184.70 ± 51.38

188.91 ± 57.34

0.91

  Red blood cell count (×1012/L)

4.48 ± 0.46

4.41 ± 0.40

4.52 ± 0.45

0.38

Preop. values (blood coagulation)

  Prothrombin time (s)

11.39 ± 0.65

11.29 ± 0.92

11.57 ± 0.84

0.17

  INR

0.98 ± 0.53

1.06 ± 0.47

1.01 ± 0.22

0.39

  APTT (s)

27.24 ± 3.68

27.92 ± 2.86

28.24 ± 3.81

0.28

  Fibrinogen (g/L)

2.97 ± 0.95

2.78 ± 0.92

2.57 ± 0.79

0.06

  D-Dimer (mg/L)

0.91 ± 1.17

1.07 ± 1.32

0.86 ± 0.87

0.54

  FDP (mg/L)

2.72 ± 2.25

3.07 ± 3.37

2.55 ± 2.19

0.55

Preop. knee function

  ROM

93.10 ± 17.41

92.48 ± 15.54

94.12 ± 16.88

0.86

  KSS

47.38 ± 9.81

46.32 ± 11.80

47.05 ± 10.02

0.85

  1. ASA = American Society of Anesthesiologists, INR = international normalized ratio, APTT = activated partial thromboplastin time, FDP = fibrinogen degradation product, ROM = range of motion, and KSS = knee society score. The values are presented as the mean and the standard deviation. The values are given as the number of patient and the percentage of the group. The p value represents the result of one-way analysis of variance for independent means for continuous variables or the chi-square test for independent proportions that included the three groups.