Figure 4

Apoptosis in PTJ64i and PTJ86i cells treated with 12.5 or 50 mM DCA. (A) Values represented in the histograms (top of each panel) are the means ± SD of two to six independent experiments (*p < 0.05; ***p < 0.001). Dot plots (bottom of each panel) show representative experiments after a 24-hour treatment with 12.5 or 50 mM DCA; (B) Expression of cytochrome C in PTJ64i and PTJ86i cells treated with 12.5 and 50 mM DCA for 8 hours was analyzed by western blot. Full-length western blots are included in Supplementary Information (Fig. S3).