Figure 8
Effect of DCA, GW6471 and metformin as single agents or in combinations on PGL cell viability. Cells were incubated for 72 hours with DCA, GW6471 and metformin, alone or in combination, at the indicated concentrations, or with vehicle. Cell viability was assessed by MTT assay. The combination index (CI) for each drug combination was calculated using the Chou–Talalay equation. Data shown are the means ± SD of three independent experiments with quintuplicate determinations.
