Figure 4

Structural alignment of DNA-free GR DBD with previous structures. (A–C) Structural alignments of the 8 monomers found in the crystal structures of free GR-DBD (in grey) overlaid with structures of DNA-bound GR DBD from crystal structures 3G99 (A) and 4HN5 (B) and DNA-free GR DBD from NMR structures 1GDC, 1RGD, and 2GDA (C).