Table 1 List of top up- and down-regulated head kidney proteins of rainbow trout in response to Yersinia ruckeri strains. Fold change (infected vs control) was statistically analysed in Y. ruckeri CSF007-82 (biotype 1) and 7959-11 (biotype 2) infected and control rainbow trout samples (n = 27).

LYSC2_ONCMY

Lysozyme C II

6

Lysozyme activity

CSF007-82

2.2

4.8*

2.2

7959-11

2.0

4.8*

1.2

Q68S98_SALSA

C type lectin receptor A

2

Carbohydrate binding

CSF007-82

2.6*

4.8*

1.4

7959-11

2.3*

3.6*

1.2

C0KIP4_ONCMY

C type lectin receptor B

4

Carbohydrate binding

CSF007-82

2.1*

4.3*

2.1

7959-11

2.0*

2.8*

1.5

Q5DVP5_ONCMY

Interleukin-16 (Fragment)

2

Cytokine activity

CSF007-82

2.1*

2.1

2.2

7959-11

2.3*

2.3

1.6

Q9PT14_ONCMY

Precerebellin-like protein

5

Response to lipopolysaccharide

CSF007-82

2.9

10.8*

2.9

7959-11

2.5

6.4*

1.9

Q9DFJ1_ONCMY

Chemotaxin (Fragment)

5

Neutrophil chemotactic activity

CSF007-82

4.1*

2.9

1.1

7959-11

2.7*

2.1

−1.3

B5XDZ7_SALSA

Catechol-O-methyltransferase domain-containing protein 1

5

O-methyltransferase activity

CSF007-82

2.4*

6.6*

2.3

7959-11

2.2*

3.3*

1.4

B5X215_SALSA

Ribonucleoside-diphosphate reductase subunit M2

4

Ribonucleoside-diphosphate reductase activity

CSF007-82

2.3*

2.2

1.1

7959-11

2.2*

1.5

−1.3

I3WWD7_ONCMY

Plasminogen activator inhibitor 1

2

Serine protease inhibitor

CSF007-82

3.2*

1.4

1.2

7959-11

2.9*

1.3

−1.1

C1BHS7_ONCMY

Protein S100

2

Calcium ion binding

CSF007-82

−1.4

−2.2*

−1.1

7959-11

−1.4

−1.6

1.1

W8W0Y8_ONCMY

Glutathione peroxidase

6

Anti-oxidant activity

CSF007-82

−1.9

−2.6*

−1.3

7959-11

−2.5

−1.4

−1.1