Table 4 Association between various combinations of family history and DM.

From: Association of Percentage Body Fat and Metabolic Health in Offspring of Patients with Cardiovascular Diseases

Combination

DM

Stroke

HTN

MI

Univariate analysisa OR (95% CI)

P Value

Multivariate analysisb OR (95% CI)

P Value

1 (N = 41885)

Reference

Reference

2 (N = 5084)

+

3.461 (2.614–4.584)

<0.001

4.366 (3.231–5.901)

<0.001

3 (N = 767)

+

0.576 (0.181–1.838)

0.351

0.489 (0.149–1.609)

0.239

4 (N = 287)

+

+

1.656 (0.505–5.426)

0.405

2.952 (0.876–9.946)

0.081

5 (N = 1320)

+

1.104 (0.587–2.076)

0.759

1.267 (0.659–2.435)

0.477

6 (N = 428)

+

+

2.636 (1.239–5.608)

0.012

2.782 (1.253–6.174)

0.012

7 (N = 123)

+

+

3.486 (1.108–11.937)

0.047

5.444 (1.545–19.182)

0.008

8 (N = 68)

+

+

 

+

2.453 (0.308–19.515)

0.396

3.986 (0.471–33.756)

0.205

9 (N = 8267)

+

1.102 (0.801–1.516)

0.550

1.200 (0.862–1.671)

0.279

10 (N = 5366)

+

+

1.963 (1.419–2.717)

<0.001

2.445 (1.735–3.445)

<0.001

11 (N = 939)

+

+

1.472 (0.732–2.959)

0.278

1.541 (0.745–3.186)

0.244

12 (N = 879)

+

+

+

1.759 (0.871–3.549)

0.115

2.836 (1.361–5.908)

0.005

13 (N = 1437)

+

+

0.721 (0.349–1.491)

0.378

0.682 (0.317–1.465)

0.327

14 (N = 1477)

+

+

+

2.944 (1.855–4.673)

<0.001

4.748 (2.910–7.745)

<0.001

15 (N = 304)

+

+

+

1.051 (0.252–4.393)

0.945

1.353 (0.315–5.807)

0.684

16 (N = 595)

+

+

+

+

0.330 (0.045–2.393)

0.273

0.521 (0.070–3.854)

0.523

  1. aAdjusted covariates: unadjusted.
  2. bAdjusted covariates: age + gender + BMI + proteinuria, serum total cholesterol, uric acid, creatinine, AST, albumin, hsCRP + history of smoking, drinking.