Figure 3 | Scientific Reports

Figure 3

From: Cellular Depletion of BRD8 Causes p53-Dependent Apoptosis and Induces a DNA Damage Response in Non-Stressed Cells

Figure 3The alternative text for this image may have been generated using AI.

BRD8 knockdown induces pro-apoptotic p53 target genes in HCT116 cells. (a–d) RT-qPCR assay showing mRNA expression levels of Puma, p53DINP1, Fas, TIGAR, Bax. Data are the mean ± SD from three independent experiments. An ANOVA test followed up with a Dunnett analysis was used to compare each mean to its relative control. *P ≤ 0.05; **P ≤ 0.01; ns = non-significant compared to relative control.

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