Figure 5

Contribution of SMA+ cells during salivary gland development. (A) Schematic depicting the experimental timeline for the genetic lineage tracing studies performed in the Acta2CreERT2;Rosa26-tdTomato mice. (B) SMA+ cells contribute exclusively to the basal and myoepithelial cell lineages. (C) Quantification of the percentage of RFP+ cells which co-express the various cell lineage markers as indicated. Data are represented as mean ± standard deviation (S.D.). Arrows highlight double positive cells as indicated. Scale bar 37 μm. TAM- tamoxifen, E-embryonic. n = 4.