Table 1 Clinical and pathological characteristics of the patients with pT3a renal cell carcinoma according to cause of pathologic T3a.
From: Accurate Risk Assessment of Patients with Pathologic T3aN0M0 Renal Cell Carcinoma
Variables | Total | EFI only | RVI only | EFI + RVI | p-value |
|---|---|---|---|---|---|
No. patients | 211 | 124 | 40 | 47 | |
Median age (year)(IQR) | 60.0 (52–69) | 58.5 (50.0–69.0) | 62.8 (54.0–71.0) | 62.7 (56.0–69.0) | 0.041 |
Female (%) | 53 (25.1) | 30 (24.2) | 13 (32.5) | 10 (21.3) | 0.509 |
Median body mass index (kg/m2)(IQR) | 23.9 (22.3–26.2) | 24.4 (22.6–26.3) | 24.5 (22.1–26.3) | 24.0 (21.7–26.2) | 0.690 |
ECOG performance status (%) | 0.475 | ||||
0–1 | 201 (95.3) | 120 (96.8) | 38 (95.0) | 44 (93.6) | |
2–3 | 10 (4.7) | 4 (3.2) | 2 (5.0) | 3 (6.4) | |
Partial nephrectomy (%) | 26 (12.3) | 22 (17.7) | 1 (2.5) | 3 (6.3) | 0.012 |
Median pathologic tumor diameter (cm)(IQR) | 6.8 (4.9–9.4) | 6.5 (4.5–9.5) | 7.2 (4.5–9.1) | 7.0 (5.0–9.4) | 0.600 |
Histological type (%) | 0.489 | ||||
Clear cell | 172 (81.5) | 100 (80.6) | 34 (85.0) | 38 (80.9) | |
Papillary | 15 (7.1) | 10 (8.1) | 1 (2.5) | 4 (8.5) | |
Chromophobe | 18 (8.5) | 11 (8.9) | 3 (7.5) | 4 (8.5) | |
Others | 6 (2.9) | 3 (2.4) | 2 (5.0) | 1 (2.1) | |
Fuhrman grade (%) | 0.195 | ||||
1–2 | 45 (20.3) | 31 (25.0) | 4 (10.0) | 9 (19.1) | |
3–4 | 166 (78.7) | 93 (75.0) | 36 (90.0) | 38 (80.9) | |
Positive surgical margin (%) | 4 (1.9) | 2 (1.6) | 1 (2.5) | 1 (2.1) | 0.939 |
Capsular invasion (%) | 152 (72.0) | 102 (82.3) | 12 (30.0) | 38 (80.9) | <0.001 |
Necrosis (%) | 103 (48.8) | 59 (47.6) | 18 (45.0) | 26 (55.3) | 0.541 |
Angiolymphatic invasion (%) | 33 (15.6) | 10 (8.1) | 9 (22.5) | 14 (29.8) | 0.001 |
Perineural invasion (%) | 6 (2.8) | 3 (2.4) | 1 (2.5) | 2 (4.3) | 0.804 |
Sarcomatoid differentiaton (%) | 26 (12.3) | 11 (8.9) | 3 (7.5) | 12 (25.5) | 0.007 |
