Table 2 Uni- and Multi-variable Cox-regression analyses on recurrence free survival.
From: Accurate Risk Assessment of Patients with Pathologic T3aN0M0 Renal Cell Carcinoma
Variables | HR (95% CI) | p-value | HR (95%CI) | p value |
|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
Age | 1.005 (0.984–1.027) | 0.650 | ||
Female | 1.905 (1.131–3.207) | 0.015 | 2.222 (1.291–3.825) | 0.003 |
Body mass index | 0.929 (0.851–1.015) | 0.101 | ||
ECOG performance status | 2.326 (0.937–6.463) | 0.105 | ||
Tumor diameter | 1.163 (1.103–1.227) | <0.001 | 1.107 (1.047–1.170) | <0.001 |
Surgical methods (RN vs PN) | 0.634 (0.273–1.474) | 0.290 | ||
Surgical margin positive | 0.955 (0.475–1.919) | 0.897 | ||
Histologic type (clear cell vs.) | 1.272 (0.700–2.313) | 0.430 | ||
Fuhrman grade (1–2 vs 3–4) | 1.624 (0.859–3.072) | 0.136 | ||
Extra-renal fat invasion | 5.154 (4.264–6.230) | <0.001 | ||
Renal venous invasion | 6.175 (5.050–7.550) | <0.001 | ||
pT3a factor (2 vs 1) | 2.254 (1.319–3.850) | 0.003 | 1.961 (1.059–3.632) | 0.032 |
Capsular invasion | 1.099 (0.624–1.935) | 0.744 | ||
Necrosis | 3.100 (2.777–3.461) | <0.001 | 3.163 (1.760–5.684) | <0.001 |
Perineural invasion | 7.681 (4.091–14.420) | <0.001 | 1.795 (0.487–6.624) | 0.380 |
Angiolymphatic invasion | 6.356 (5.004–8.074) | <0.001 | 1.923 (0.985–3.753) | 0.055 |
Sarcomatoid differentiation | 1.412 (1.305–1.529) | <0.001 | 1.409 (0.694–2.863) | 0.343 |
