Figure 2

Longitudinal monitoring of activation of the Col1α1 promoter in transgenic rats after rotator cuff injury. (a) Transverse serial SPECT/CT fusion images from a Col1α1 transgenic rat with RC injury (left shoulder) allows in depth analysis of areas of high Col1α1 activity as indicated by high tracer uptake. (b) Longitudinal SPECT/CT images from three transgenic rats during acute and recovery phases of RC injury on the left shoulder. Right shoulder was not injured and serves as the negative control.