Figure 1 | Scientific Reports

Figure 1

From: Predilection of Low Protein C-induced Spontaneous Atherothrombosis for the Right Coronary Sinus in Apolipoprotein E deficient mice

Figure 1

Atherothrombosis in the aortic root of siProc treated Apoe−/− mice. (A) Representative section of the aortic root of a mouse treated with siNEG. (B) Representative section of the aortic root of a mouse treated with siProc, without a thrombus (siProc − THR). (C and D) Representative section of the aortic root of a mouse treated with siProc, with a thrombus associated with an atherosclerotic plaque (siProc + THR, panel D is a magnification of the black square in panel C). (E) Representative section of the common carotid artery containing an atherosclerotic lesion upon collar placement, derived from an siProc treated mouse. (F) A thrombus-like structure associated with an atherosclerotic lesion in the common carotid artery. All sections are hematoxylin and eosin (HE) stained. The scattered black lines in panels A, B, and C mark borders of the plaque. LCS: Left coronary sinus, NCS: Non-coronary sinus, RCS: Right coronary sinus. *Thrombus. Black bars represent 200 μm.

Back to article page