Table 4 Molecular alterations in IM among the Hp, AG, and GC groups.
No. of IM samples | Hp group | AG group | GC group | Hp vs AG group | GC vs AG group | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
n = 21 | (%) | n = 23 | (%) | n = 35 | (%) | P | P | OR (95% CI) | ||||
MSI | 8 | (38.1) | 4 | (17.4) | 5 | (14.3) | 0.18 | 1 | ||||
CIMP | 7 | (33.3) | 3 | (13.0) | 19 | (54.3) | 0.16 | 0.002 | 7.92 (1.98–31.60) | |||
Estimate | SE | P | Estimate | SE | P | |||||||
CDH1 | 7 | (33.3) | 2 | (8.7) | 7 | (20.0) | 0.33 | 0.13 | 0.01 | 0.11 | 0.12 | 0.35 |
CDKN2A | 0 | (0) | 1 | (4.3) | 0 | (0) | −0.03 | 0.03 | 0.26 | −0.03 | 0.02 | 0.20 |
MLH1 | 0 | (0) | 0 | (0) | 0 | (0) | — | — | — | — | — | — |
MGMT | 0 | (0) | 0 | (0) | 3 | (8.6) | 0.04 | 0.07 | 0.56 | 0.10 | 0.06 | 0.11 |
MINT1 | 13 | (61.9) | 18 | (78.3) | 26 | (74.3) | −0.15 | 0.15 | 0.30 | −0.02 | 0.13 | 0.85 |
MINT31 | 12 | (57.1) | 10 | (43.5) | 24 | (68.6) | 0.19 | 0.16 | 0.24 | 0.27 | 0.14 | 0.07 |
RUNX3 | 6 | (28.6) | 5 | (21.7) | 17 | (48.6) | 0.05 | 0.14 | 0.71 | 0.23 | 0.12 | 0.07 |
miR-124a-3 | 21 | (100) | 19 | (86.4)a | 31 | (88.6) | 0.13 | 0.11 | 0.24 | −0.02 | 0.09 | 0.85 |
miR-34c | 13 | (61.9) | 12 | (54.5)b | 20 | (58.8)c | −0.01 | 0.17 | 0.95 | −0.01 | 0.15 | 0.92 |
