Table 2 Correlations between Patient Data and Serum OPG levels.

From: Osteoprotegerin and Myocardial Fibrosis in Patients with Aortic Stenosis

Variable

Spearman’s Correlation with OPG

P-Value

Patient Demographics

Age, years

0.56

<0.0001*

Male, n (%)

−0.025

0.80

Hypertension, n (%)

−0.047

0.63

SBP, mmHg

0.015

0.88

DBP, mmHg

−0.13

0.19

Diabetes mellitus, n (%)

0.024

0.82

Current smoker, n (%)

0.005

0.96

Any coronary artery disease, n (%)

0.10

0.29

Previous stroke, n (%)

0.0009

0.99

Atrial Fibrillation, n (%)

−0.023

0.82

Hypercholesterolaemia, n (%)

0.028

0.78

NYHA ≥ II

0.033

0.73

Height, cm

−0.17

0.077

Weight, kg

−0.37

<0.0001*

BMI, kg/m2

−0.36

<0.001*

Pharmacotherapy

Aspirin, n (%)

0.006

0.95

Clopidogrel, n (%)

0.046

0.65

ACE-I/ARB, n (%)

−0.11

0.26

Beta Blocker, n (%)

−0.098

0.33

Calcium channel blocker, n (%)

−0.25

0.014*

Diuretic, n (%)

0.25

0.009*

Warfarin, n (%)

0.061

0.55

Amiodarone, n (%)

−0.071

0.48

Statin, n (%)

−0.046

0.64

Biochemical Data

Creatinine, μmol/L

0.32

0.001*

NT-ProBNP (pg/mL)

0.30

0.002*

CRP (mg/L)

0.22

0.038*

CMR Data

CMR aortic valve area, cm2

−0.24

0.011*

LVEF, %

−0.041

0.67

LV Mass, g

−0.22

0.021*

LGE Mass

0.22

0.027*

LGE Percent

0.25

0.010*

  1. *p < 0.05. Correlation between Patient Data and Serum OPG Levels. ACE-I, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; BMI, body mass index; CMR, cardiovascular magnetic resonance; DBP, diastolic blood pressure; LGE, late gadolinium enhancement; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association; SBP, systolic blood pressure.
Back to article page