Table 1 Inhibition of pathogen-mediated cell damage to human THP-1 cells by F19 and F12.
% Damage (LDH Leakage) | ||||||
|---|---|---|---|---|---|---|
|  | (µg/mL) | MRSA USA300 | MRSE Q-15 | Streptococcus pyogenes AC7 | Streptococcus pneumoniae NR13395 | Bacillus cereus |
Control | 0 | 100.0 ± 1.0 | 100.0 ± 1.7 | 100.0 ± 4.0 | 106.7 ± 5.3 | 100.0 ± 3.3 |
F19 | 1 | 62.0 ± 0.6 | 85.5 ± 2.6 | — | 95.3 ± 1.1 | — |
5 | — | 62.6 ± 1.1 | 97.4 ± 0.7 | 72.9 ± 1.1 | — | |
10 | 44.2 ± 2.0 | 48.1 ± 1.1 | 88.4 ± 1.9 | 48.6 ± 1.8 | — | |
20 | — | 26.5 ± 0.5 | 73.6 ± 0.5 | 39.6 ± 0.6 | — | |
30 | — | 22.1 ± 0.6 | 56.2 ± 3.4 | — | 63.7 ± 1.3 | |
40 | — | 19.6 ± 1.1 | 38.7 ± 1.8 | — | 52.0 ± 0.1 | |
50 | 29.1 ± 1.6 | — | — | 40.2 ± 0.8 | 69.7 ± 1.2 | |
0 | — | 100.0 ± 1.2 |  |  |  | |
1 | — | 85.1 ± 1.0 |  |  |  | |
5 | — | 71.9 ± 3.2 |  |  |  | |
10 | — | 35.4 ± 0.5 |  |  |  | |
F12 | 20 | — | 24.3 ± 0.5 |  |  |  |
30 | — | 22.4 ± 0.4 |  |  |  | |
40 | — | 19.2 ± 1.1 |  |  |  | |
50 | 20 ± 3.5 | — |  |  |  | |
