Table 3 Associations between relative telomere length in peripheral blood leukocytes and GCA risk stratified by age, sex, smoking, and drinking status.

	RTL	Controls		Cases		OR (95% CI)	P value^a
	RTL	N	%	N	%	OR (95% CI)	P value^a
Age (years)
<60	Long	94	66.67	66	46.81	1.00
<60	Short	47	33.33	75	53.19	2.14 (1.27–3.60)	0.004
≥60	Long	161	43.63	135	35.25	1.00
	Short	208	56.37	248	64.75	1.38 (1.01–1.88)	0.042
	P value^b	4.54 × 10⁻⁶		0.020
Sex
Male	Long	216	49.66	192	42.57	1.00
Male	Short	219	50.34	259	57.43	1.43 (1.07–1.92)	0.016
Female	Long	39	52.00	36	49.32	1.00
	Short	36	48.00	37	50.68	1.17 (0.59–2.36)	0.652
	P value^b	0.803		0.131
Smoking status
No	Long	203	50.88	112	41.64	1.00
No	Short	196	49.12	157	58.36	1.59 (1.14–2.22)	0.007
Yes	Long	52	46.85	83	34.16	1.00
	Short	59	53.15	160	65.84	2.21 (1.35–3.64)	0.002
	P value^b	0.520		0.084
Drinking status
No	Long	162	47.23	116	39.46	1.00
No	Short	181	52.77	178	60.54	1.58 (1.14–2.20)	0.007
Yes	Long	93	55.69	77	35.98	1.00
	Short	74	44.31	137	64.02	2.18 (1.33–3.60)	0.002
	P value^b	0.089		0.459

Abbreviations: GCA, gastric cardia adenocarcinoma; RTL, Relative Telomere length; OR, odds ratio; CI, confidence interval; SD, standard deviation.
^aP values and ORs were adjusted for age, sex, smoking and drinking status with a logistic regression model.
^bP values were calculated by Pearson chi-square tests for age, sex, smoking and drinking status.

Quick links

Search