Table 2 Median parameter estimates from fits with the three different compartment models in every patient, together with SUV_max and SUV-to-background ratio (SUR): K₁ and k₂ from the simplified 1TCM; K₁, k₂ and V_B from the standard 1TCM; K₁, k₂, k₃, k₄ and V_B from the 2TCM.

Grade	SUV_max	SUR	s1TCM		1TCM			2TCM
Grade	SUV_max	SUR	K₁[10⁻² min⁻¹]	k₂[10⁻² min⁻¹]	K₁[10⁻² min⁻¹]	k₂[10⁻² min⁻¹]	V_B[ml/100 ml]	K₁[10⁻² min⁻¹]	k₂[10⁻² min⁻¹]	k₃[10⁻² min⁻¹]	k₄[10⁻² min⁻¹]	V_B [ml/100 ml]
III	1.7	2.1	6.6	10.4	4.9	6.8	4.2	9.3	59.2	18.4	4.1	2.2
	3.9	3.4	12.4	9.2	10.3	6.8	6.7	13.7	33.1	23.0	7.0	5.1
	1.9	1.6	7.3	11.8	4.5	6.2	7.9	7.4	34.4	15.2	3.7	6.6
	1.1	1.2	15.3	39.2	4.3	7.3	8.6	7.2	45.8	28.8	7.7	7.3
	3.3	2.7	18.9	15.1	14.7	10.7	9.3	22.2	47.2	19.0	8.7	5.9
	3.0	3.1	27.2	26.5	16.4	13.4	10.3	19.4	32.8	28.3	17.2	9.4
	1.2	1.4	8.9	20.5	4.6	9.3	5.7	9.6	100	30.6	6.7	4.8
IV	1.9	1.7	23.9	43.3	7.2	8.7	12.6	10.1	51.8	35.1	7.5	11.4
	2.9	3.7	42.7	33.8	33.3	22.5	14.7	47.9	100	22.1	13.7	11.5
	4.6	3.2	23.2	15.6	14.8	7.5	15.9	21.8	49.8	44.8	8.4	13.4
	3.3	2.9	22.6	18.0	18.5	13.5	9.8	38.7	100	17.5	6.7	6.9
	3.4	4.1	17.1	15.3	12.6	9.6	11.5	20.4	46.7	18.5	7.4	8.8
	2.9	3.0	11.7	7.5	9.0	4.5	11.2	17.5	63.4	26.3	2.2	7.2
	3.4	3.4	13.9	11.0	9.9	6.5	8.7	20.0	97.9	30.6	5.9	5.8
	1.9	2.6	12.7	17.5	5.8	5.0	9.4	8.5	56.2	56.3	6.6	9.1
	2.8	2.6	14.7	14.7	10.4	7.4	10.4	16.2	42.3	23.8	7.5	7.7

Note: Median Parameter estimates were used instead of averages, due to several voxels with failed fits, which yielded outliers towards high transfer rates (~100 10⁻² min⁻¹ was set as upper constraint for all parameters).

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