Figure 5
Phenotypic and genetic analysis of ß-lactam genes. (A) A heatmap of three ß-lactam associated genes shows the down regulation (red) of carO and the up regulation (green) of ampC and blaOXA51-like. (B) Disk-diffusion assays were performed and changes in the halo of inhibition were recorded for cefazolin (CZ), ampicillin (AMP), ceftazidime (CAZ), cefepime (FEP), imipenem (IMP) and meropenem (MEM). The photographs depict the results of (C) an imipenem (IPM) disk diffusion assay and (D) a meropenem (MP) E-test assay for A118 cells cultured with and without HSA.
