Table 3 Comparison of separation results for different chiral separators utilizing CNTs, GO, and graphene.
Separator type | CNT-doped organic polymer monolith (ref.25) | Glutamic acid-modified GO separation membrane (ref.37) | Alanine racemase chiral analogue-coated mesoporous carbon monolith (refs39,40) | Carbon nanoparticle-modified separation system with dextrin (ref.27) | MOD1 mesoporous 3D GNS | MOD3 Mesoporous 3D GNS |
|---|---|---|---|---|---|---|
Reported selectivity α | 1.1 ÷ 2.89 depending on separated compound | 2 (max) |  | 1 ÷ 2.5 depending on separated compound | 17.5 (for thalidomide) | 12.5 (for ibuprofen) |
Reported resolution Rs or degree of separation | 1.31 ÷ 2.87 depending on separated compound |  | 90–95% separation | 0.8–4.3 depending on separated compound | baseline separation for 0.05 mg/ml of thalidomide | baseline separation for 0.8 mg/ml of ibuprofen |
Separated chiral compound | Celiprolol, chlorpheniramine, cizolirtine and others (ref.25) | D,L-DOPA (see ref.37) | Phenylalanine, serine, tryptophan | Sulconazole, ketoconazole, citalopram hydrochloride, nefopam hydrochloride | thalidomide, ibuprofen | ibuprofen, thalidomide |
Functional role and separation technique it is designed for | Chiral stationary phase for HPLC | Membrane material for membrane filtration | Adsorbing material, adsorption | Electrode material for capillary electro kinetic chromatography | Chiral stationary phase for HPLC | Chiral stationary phase for HPLC |
