Table 2 Patients’ serum samples.

From: Increased levels of circulating MMP3 correlate with severe rejection in face transplantation

Patient

Posttransplant month

Histological Banff grade

Status

Clinical presentation

MMP3 ELISA (ng/ml)

Rejection management

Patient 1

12

I

NR

NA

6.04

NA

Patient 1

17

II

NSR

erythema and edema, mucosa lesion

14.37

maintenance immunosuppression adjustment, topical therapy

Patient 1

24

0

NR

NA

7.34

NA

Patient 1

30

III

NSR

subclinical

7.75

maintenance immunosuppression adjustment

Patient 1

42

I

NR

NA

7.3

NA

Patient 2

18

0

NR

NA

11.33

NA

Patient 2

23

II

SR

erythema and edema

70.77

steroid bolus

Patient 2

24

III

SR

erythema and edema

124.6

ATG

Patient 2

48

III

SR

erythema and edema

193.86

steroid bolus

Patient 2

54

I

NR

NA

20.47

NA

Patient 3

12

0

NR

NA

16.66

NA

Patient 3

18

III

SR

exanthema

79.14

steroid bolus

Patient 3

34

III

SR

erythema

24.53

steroid bolus

Patient 3

54

0

NR

NA

20.65

NA

Patient 4

6

I

NR

NA

21.96

NA

Patient 4

13

III

NSR

erythema and edema

18.03

topical therapy

Patient 4

18

0

NR

NA

29.84

NA

Patient 4

24

III

NSR

erythema and edema

39.43

topical therapy

Patient 5

6

I

NR

NA

31.31

NA

Patient 5

7

III

SR

erythema and edema

105.82

steroid bolus, ATG, IVIG

Patient 5

9

I

NR

NA

49.12

NA

Patient 5

12

III

NSR

hyperpigmentation

43.88

maintenance immunosuppression adjustment, topical therapy

Patient 6

3

II

NR

NA

45.92

NA

Patient 6

12

0

NR

NA

23.76

NA

  1. All rejection samples were from cell-mediated rejections. ATG, anti-thymoglobulin; IVIG, intravenous immunoglobulin; NA, not applicable; NR, no-rejection; NSR, nonsevere rejection; SR, severe rejection.