Table 1 Biological activities of antibiotics and peptides used in the study.
From: Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms
cell | Compound | ||||||
|---|---|---|---|---|---|---|---|
daptomycin | tetracycline | ceftriaxone | CecB | CecM | ChoC | ChoM | |
Minimum inhibitory concentrations, µM | |||||||
P. aeruginosa | >100 | <6 | >25 | <1.5 | <1.5 | <1.5 | <1.5 |
S. aureus | <7 | <0.5 | <3 | >100 | >25 | >100 | <3 |
E. coli | >100 | <1.5 | <6 | <1 | <1.5 | <6 | <3 |
B. subtilis | <7 | <0.5 | <1 | >50 | <7 | <5 | <1.5 |
S. typhimurium | >60 | <1 | <1 | <3 | <1 | >12 | <3 |
M. luteus | <15 | <0.5 | <0.5 | <1 | <1 | <1 | <0.5 |
|  | (LC50)a, µM |  | |||||
HE b | >250c | UD | UD | >250d | >250d | >250d | >250d |
