Figure 2 | Scientific Reports

Figure 2

From: Pro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis – Tampere Vascular Study

Figure 2

POMC expression in human atherosclerotic plaques is positively correlated with M1 and M2 macrophage markers and negatively with smooth muscle cell markers. (A–C) Correlation between POMC mRNA levels and established M1 (grey columns) and M2 (black columns) macrophage markers in carotid (A), abdominal (B) and femoral (C) plaque samples. (D–F) Correlation between POMC mRNA levels and smooth muscle cell markers in carotid (A), abdominal (B) and femoral (C) plaque samples. Pearson correlation coefficient (r) values are presented in the column graphs. *P < 0.05, **P < 0.01 and ***P < 0.001 for correlation significances.

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