Table 5 Toxicities of induction chemotherapy and radiotherapy.
Toxicities | Toxicity Grade | P value | ||||
|---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | TPF vs GP | |
The toxicities of IC | ||||||
Leukopenia | 21 (18.6%) | 21 (18.6%) | 54 (47.8%) | 17 (15.0%) | 0 (0.0%) | 0.189 |
Thrombocytopenia | 78 (69.0%) | 24 (21.2%) | 7 (6.2%) | 3 (2.7%) | 1 (0.9%) | 0.794 |
Hemoglobin reduction | 63 (55.8%) | 48 (42.5%) | 2 (1.8%) | 0 (0.0%) | 0 (0.0%) | 0.176 |
Nausea and vomiting | 55 (48.7%) | 49 (43.4%) | 8 (7.1%) | 1 (0.9%) | 0 (0.0%) | 0.179 |
Diarrhea | 106 (95.6%) | 4 (3.5%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0.203 |
Hearing loss | 110 (97.3%) | 3 (1.8%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0.523 |
Rash | 97 (85.8%) | 13 (11.5%) | 3 (2.7%) | 0 (0.0%) | 0 (0.0%) | 0.414 |
Alanine aminotransferase | 80 (70.8%) | 27 (23.9%) | 6 (5.3%) | 0 (0.0%) | 0 (0.0%) | 0.125 |
Aspartate aminotransferase | 89 (78.8%) | 18 (15.9%) | 6 (5.3%) | 0 (0.0%) | 0 (0.0%) | 0.039 |
The acute toxicities of radiotherapy | ||||||
Dermatitis | 107 (94.7%) | 3 (2.7%) | 3 (2.7%) | 0 (0.0%) | 0 (0.0%) | 0.114 |
Mucositis | 84 (74.3%) | 23 (20.4) | 6 (5.3) | 0 (0.0%) | 0 (0.0%) | 0.740 |
Dysphagia | 99 (87.6%) | 13 (11.5%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0.481 |
The late toxicities of radiotherapy | ||||||
Xerostomia | 106 (93.8%) | 6 (5.3%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0.773 |
Neck fibrosis | 110 (97.3%) | 3 (2.7%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.592 |
Trismus | 112 (99.1%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.330 |
Hearing impairment | 103 (91.2%) | 6 (5.3%) | 4 (3.5%) | 0 (0.0%) | 0 (0.0%) | 0.544 |
Cerebral injury | 112 (99.1%) | 1 (0.9%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.330 |
Cranial nerve palsy | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1.000 |
