Figure 6
From: LncRNA BLAT1 is Upregulated in Basal-like Breast Cancer through Epigenetic Modifications
Bisulfite sequencing of the BLAT1 promoter in BLBC cell lines. (A,B) Bisulfite sequencing of three CpG sites (cg20599967, cg19957905, and cg18250846) showed a lower percentage of methylation in basal-like breast cancer (BLBC) cell lines, compared to the non-BLBC cell lines. (C) Inhibition of methylation with 5-Aza-2′-deoxyctidine (5′-Aza) led to a significant increase in BLAT1 expression in MDA-MB-468 and UACC-3199 cells. Error bars, SE (***p < 0.001 or **p < 0.01 vs. DMSO treated cells).
