Figure 3 | Scientific Reports

Figure 3

From: RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr−/− mice

Figure 3

Atherosclerotic plaque size and inflammatory state is unaffected by RAGE. (A,B) Representative pictures (A) of H&E-stained aortic root plaques (40x magnification) and corresponding quantification of plaque size (B) after 12 weeks of WTD feeding. (C) Plaque phenotype score presented as percentage of each score. (D) Quantification of plaque collagen content presented as percentage of plaque size area. (E) Aortic arch gene expression levels of inflammatory and immune cell specific markers. All data are means ± SEM. n = 11–12. Scalebars 100 µm.

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