Figure 3

Characteristics of the three miRNAs associated with poor prognoses. (a) Density scatter plots showing the association between miRNA (miR-296-5p, miR-324-3p, and miR-3928-3p) expression and CNV in the precursor locus, particularly for copy number gains. The curved line was estimated with R function “lowess”. (b) Boxplots showing the higher expression of the three miRNAs of interest in Sq samples relative to those in Ad and normal (N) samples. P-values were calculated with the Wilcoxon rank sum test: (*) P-value < 0.05; (**) P-value < 0.01.