Table 3 Sensitivity, specificity and accuracy values of drug resistance prediction by high confidence mutations inferred to be associated with antibiotic resistance in isolates within the data set with DST results from the BACTEC MGIT 960 Mycobacteria liquid culture method.

From: Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase

Drug

TP

FP

TN

FN

Sensitivity

95%CI Low

95% CI High

Specificity

95%CI Low

95%CI High

Accuracy (%)

Isoniazid

321

1

463

41

0.887

0.848

0.917

0.997

0.986

0.999

94.9

Levofloxacin

23

10

313

2

0.92

0.725

0.986

0.969

0.942

0.984

96.6

Ofloxacin

35

1

312

2

0.946

0.805

0.991

0.997

0.978

0.999

99.1

Rifampicin

275

2

533

19

0.935

0.899

0.96

0.996

0.985

0.999

97.5

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