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Figure 1

From: Whole-volume ADC Histogram and Texture Analyses of Parotid Glands as an Image Biomarker in Evaluating Disease Activity of Primary Sjögren’s Syndrome

Figure 1

(AC) Axial diffusion-weighted imaging (DWI) scan (b = 1000 s/mm2), corresponding to the apparent diffusion coefficient (ADC) map, and histogram of the bilateral parotid glands of an 18-year-old woman with low-activity primary Sjögren’s syndrome (pSS). Her European League Against Rheumatism (EULAR) pSS disease activity index (ESSDAI) score was 4 (haematological score 2+ serum biomarker score 2). MRI morphology, ANA, anti-SSA, X-ray sialography, and lip biopsy showed positive findings, whereas her anti-SSB and ocular tests were negative. The parotid ADC, ADCmean, skewness, kurtosis, and entropy values were 959.1 × 10−6 mm2/s, 1006.2 × 10−6 mm2/s, −0.177, 4.746, and 5.690, respectively. (DF) Axial DWI scan (b = 1000 s/mm2), corresponding to the ADC map, and histogram of the bilateral parotid glands in a 66-year-old woman with moderate-activity pSS. Her ESSDAI score was 6 (haematological test, serum biological marker score 2 and constitutional symptoms, articular score 1). MRI morphology, ANA, anti-SSA, anti-SSB, and X-ray sialography showed positive findings, whereas the ocular tests and lip biopsy were negative. The ADC, ADCmean, skewness, kurtosis, and entropy values were 943.0 × 10−6 mm2/s, 1015.6 × 10−6 mm2/s, 0.359, 5.254, and 6.181, respectively. Note the dashed lines covering the edge of the right parotid glands.

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