Table 1 The parotid magnetic resonance imaging (MRI) indexes of patients with primary Sjögren’s syndrome having different activities.

From: Whole-volume ADC Histogram and Texture Analyses of Parotid Glands as an Image Biomarker in Evaluating Disease Activity of Primary Sjögren’s Syndrome

Index

Low-activity group (n = 35)

Moderate–high activity group (n = 20)

P

MRI morphology (positive/negative)

10/25

16/4

0.001*

ADC (×10−6 mm2/s)

826.5 ± 109.8

713.6 ± 169.2

0.004*

Parotid volume (mm3)

3281.5 ± 1163.5

3904.8 ± 1983.4

0.244

ADCmean (×10−6 mm2/s)

835.3 ± 125.3

733.0 ± 177.8

0.042*

Skewness

0.3 ± 0.4

0.4 ± 0.4

0.484

Kurtosis

4.6 ± 1.2

4.1 ± 1.0

0.094

Entropy

5.9 ± 0.2

6.2 ± 0.3

<0.001*

  1. Note, ADC, the mean apparent diffusion coefficient (ADC) value, obtained from one region of interest (ROI) in single slice. ADCmean, the mean value of all ADC values within the volume of interest (VOI). Skewness, the histogram asymmetry degree around the mean. Kurtosis, a measurement of the histogram sharpness. Entropy, the distribution of gray levels within the VOI. *P < 0.05.
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