Table 5 The clinical, systemic, and laboratory characteristics of patients with primary Sjögren’s syndrome having different activities

From: Whole-volume ADC Histogram and Texture Analyses of Parotid Glands as an Image Biomarker in Evaluating Disease Activity of Primary Sjögren’s Syndrome

Index

Low activity (n = 35)

Moderate–high activity (n = 20)

ESSDAI score

2.4 ± 1.4

5.2 ± 1.2

Age (year)

46.6 ± 13.4

47.3 ± 17.5

Disease duration (year)

3.8 ± 5.1

3.8 ± 6.1

Female/male

34/1

19/1

Oral dryness (+)

30 (85.7%)

20 (100.0%)

Ocular dryness (+)

18 (51.4%)

9 (45.0%)

ANA (+)

31 (88.6%)

16 (80.0%)

Anti-SSA (+)

26 (74.3%)

16 (80.0%)

Anti-SSB (+)

4 (11.4%)

13 (65.0%)

X-ray sialography (+)

23 (65.7%)

18 (90.0%)

Ocular tests (+)

23 (65.7%)

11 (55.0%)

Lip biopsy (+)

13 (37.1%)

16 (80.0%)

Constitutional symptoms (+)

4 (11.4%)

12 (60.0%)

Lymphadenopathy (+)

5 (14.3%)

6 (30.0%)

Glandular injury (+)

Articular injury (+)

4 (11.4%)

2 (10.0%)

Cutaneous injury (+)

3 (8.5%)

3 (15.0%)

Pulmonary injury (+)

4 (11.4%)

9 (45.0%)

Renal injury (+)

2 (5.7%)

0 (0.0%)

Muscular injury (+)

4 (11.4%)

2 (10.0%)

Peripheral nervous system injury (+)

1 (2.9%)

1 (5.0%)

Central nervous system injury (+)

0(0.0%)

0 (0.0%)

Hematological test (+)

13 (37.1%)

15 (75.0%)

Serum biomarkers (+)

20 (57.1%)

16 (80.0%)

  1. Note, ESSDAI, the European League Against Rheumatism (EULAR) SS disease activity index. Constitutional symptoms include fewer, night sweats, and weight loss. Hematological tests include neutropenia, anemia, and thrombocytopenia. Serum biomarkers include C3, C4, CH50, and IgG.