Table 1 Performance comparisons between the index test method (IS4), the reference qPCR (CTM assay), and culture under different conditions, including overall specimens, pulmonary specimens (sputum and bronchoalveolar lavage (BAL)), extrapulmonary specimens, AFS-positive specimens and AFS-negative specimens.
CTM+ | CTM− | Culture+ | Culture− | |
|---|---|---|---|---|
Overall specimens (Sample size: 130) | ||||
IS4+ | 35 | 16 | 35 | 16 |
IS4− | 1 | 78 | 3 | 76 |
CTM+ | — | — | 32 | 4 |
CTM− | — | — | 6 | 88 |
On pulmonary specimens (Sample size: 64) | ||||
IS4+ | 22 | 10 | 23 | 9 |
IS4− | 1 | 31 | 2 | 30 |
CTM+ | — | — | 22 | 1 |
CTM− | — | — | 3 | 38 |
On extrapulmonary specimens (Sample size: 66) | ||||
IS4+ | 13 | 6 | 12 | 7 |
IS4− | 0 | 47 | 1 | 46 |
CTM+ | — | — | 10 | 3 |
CTM- | — | — | 3 | 50 |
On AFS-positive specimens (Sample size: 22) | ||||
IS4+ | 17 | 1 | 16 | 2 |
IS4− | 1 | 3 | 1 | 3 |
CTM+ | — | — | 16 | 2 |
CTM− | — | — | 1 | 3 |
On AFS-negative specimens (Sample size: 108) | ||||
IS4+ | 18 | 15 | 19 | 14 |
IS4− | 0 | 75 | 2 | 73 |
CTM+ | — | — | 16 | 2 |
CTM− | — | — | 5 | 85 |
