Figure 1 | Scientific Reports

Figure 1

From: Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma

Figure 1

Gene overlap analysis of YAP1 S127A and KRAS G12V-induced rhabdomyosarcomas. (A) Venn diagram displaying the number of genes modulated by YAP1 S127A and/or KRAS G12V- induced rhabdomyosarcomas versus differentiated skeletal muscle (Up-reg: up-regulated, down-reg: down-regulated). (B) Overlap of common up-regulated or down-regulated genes in both YAP1 S127A and KRAS G12V-induced rhabdomyosarcoma with top 100 or bottom 100 genes best associated with poor survival in 18,000 cases of human cancer.

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