Table 4 Predictors of all-cause in-hospital death in haemodynamically stable PE patients with syncope aged 18 years and older (uni-variate and multi-variate logistic regression model).

From: Syncope in haemodynamically stable and unstable patients with acute pulmonary embolism – Results of the German nationwide inpatient sample

Parameters

PE + Syncope aged 18 years and older (n = 6,792 patients with syncope; 435 patients [6.4%] died in-hospital)

Univariate regression model

Multi-variate regression model

OR (95% CI)

P-value

OR (95% CI)

P-value

Age

1.058 (1.047–1.069)

<0.001

1.057 (1.045–1.070)

<0.001

Female gender

1.030 (0.846–1.254)

0.766

1.004 (0.812–1.240)

0.972

Obesity

0.558 (0.364–0.857)

0.008

0.754 (0.482–1.179)

0.216

VTE risk factors

Surgery during in-hospital stay

0.624 (0.510–0.763)

<0.001

0.526 (0.424–0.654)

<0.001

Cancer

2.901 (2.319–3.628)

<0.001

4.218 (3.300–5.393)

<0.001

Comorbidities

Coronary artery disease

1.311 (1.024–1.680)

0.032

1.163 (0.893–1.513)

0.262

Heart failure

1.990 (1.623–2.441)

<0.001

1.511 (1.211–1.887)

<0.001

Chronic lung disease

1.172 (0.910–1.509)

0.218

0.986 (0.755–1.287)

0.915

Essential arterial hypertension

0.798 (0.657–0.971)

0.024

0.689 (0.562–0.846)

<0.001

Renal insufficiency

1.903 (1.559–2.323)

<0.001

1.271 (1.021–1.581)

0.032

Diabetes mellitus

1.280 (1.021–1.604)

0.032

1.152 (0.907–1.462)

0.247

Coagulation abnormalities

1.610 (1.168–2.219)

0.004

1.664 (1.183–2.341)

0.003

Stroke

1.623 (0.864–3.049)

0.132

1.743 (0.896–3.389)

0.102

Atrial fibrillation or flutter

1.742 (1.392–2.180)

<0.001

1.322 (1.041–1.678)

0.022

Vestibular disorder

Not calculable

 

Not calculable

 

Carotid-sinus-syndrome

Not calculable

 

Not calculable

 

Meningioma

0.859 (0.114–6.472)

0.883

0.836 (0.103–6.781)

0.867

Pneumonia

1.417 (1.114–1.803)

0.005

1.341 (1.041–1.728)

0.023

Sick-sinus-syndrome

0.625 (0.229–1.709)

0.360

0.592 (0.211–1.657)

0.318

Ventricular tachycardia caused by reentry tachycardia

14.645 (0.914–234.539)

0.058

8.271 (0.451–151.552)

0.154

Pacemaker or internal cardiac defibrillator malfunction

Not calculable

 

Not calculable

 

Risk stratification parameters

Tachycardia

1.031 (0.555–1.916)

0.922

0.886 (0.452–1.736)

0.724

Right ventricular dysfunction

2.016 (1.656–2.454)

<0.001

2.136 (1.733–2.633)

<0.001

  1. Abbreviations: PE indicates for pulmonary embolism; VTE, venous thromboembolism.