Table 4 Predictors of all-cause in-hospital death in haemodynamically stable PE patients with syncope aged 18 years and older (uni-variate and multi-variate logistic regression model).
Parameters | PE + Syncope aged 18 years and older (n = 6,792 patients with syncope; 435 patients [6.4%] died in-hospital) | |||
|---|---|---|---|---|
Univariate regression model | Multi-variate regression model | |||
OR (95% CI) | P-value | OR (95% CI) | P-value | |
Age | 1.058 (1.047–1.069) | <0.001 | 1.057 (1.045–1.070) | <0.001 |
Female gender | 1.030 (0.846–1.254) | 0.766 | 1.004 (0.812–1.240) | 0.972 |
Obesity | 0.558 (0.364–0.857) | 0.008 | 0.754 (0.482–1.179) | 0.216 |
VTE risk factors | ||||
Surgery during in-hospital stay | 0.624 (0.510–0.763) | <0.001 | 0.526 (0.424–0.654) | <0.001 |
Cancer | 2.901 (2.319–3.628) | <0.001 | 4.218 (3.300–5.393) | <0.001 |
Comorbidities | ||||
Coronary artery disease | 1.311 (1.024–1.680) | 0.032 | 1.163 (0.893–1.513) | 0.262 |
Heart failure | 1.990 (1.623–2.441) | <0.001 | 1.511 (1.211–1.887) | <0.001 |
Chronic lung disease | 1.172 (0.910–1.509) | 0.218 | 0.986 (0.755–1.287) | 0.915 |
Essential arterial hypertension | 0.798 (0.657–0.971) | 0.024 | 0.689 (0.562–0.846) | <0.001 |
Renal insufficiency | 1.903 (1.559–2.323) | <0.001 | 1.271 (1.021–1.581) | 0.032 |
Diabetes mellitus | 1.280 (1.021–1.604) | 0.032 | 1.152 (0.907–1.462) | 0.247 |
Coagulation abnormalities | 1.610 (1.168–2.219) | 0.004 | 1.664 (1.183–2.341) | 0.003 |
Stroke | 1.623 (0.864–3.049) | 0.132 | 1.743 (0.896–3.389) | 0.102 |
Atrial fibrillation or flutter | 1.742 (1.392–2.180) | <0.001 | 1.322 (1.041–1.678) | 0.022 |
Vestibular disorder | Not calculable | Not calculable | ||
Carotid-sinus-syndrome | Not calculable | Not calculable | ||
Meningioma | 0.859 (0.114–6.472) | 0.883 | 0.836 (0.103–6.781) | 0.867 |
Pneumonia | 1.417 (1.114–1.803) | 0.005 | 1.341 (1.041–1.728) | 0.023 |
Sick-sinus-syndrome | 0.625 (0.229–1.709) | 0.360 | 0.592 (0.211–1.657) | 0.318 |
Ventricular tachycardia caused by reentry tachycardia | 14.645 (0.914–234.539) | 0.058 | 8.271 (0.451–151.552) | 0.154 |
Pacemaker or internal cardiac defibrillator malfunction | Not calculable | Not calculable | ||
Risk stratification parameters | ||||
Tachycardia | 1.031 (0.555–1.916) | 0.922 | 0.886 (0.452–1.736) | 0.724 |
Right ventricular dysfunction | 2.016 (1.656–2.454) | <0.001 | 2.136 (1.733–2.633) | <0.001 |