Table 3 Publications investigating EVs from cardiac progenitor cells (CPCs).

From: Evaluation of the cardioprotective potential of extracellular vesicles – a systematic review and meta-analysis

Ref.

PM

Size

Injury model

Main effector

EV marker

Barile et al.13

Precipitation, UC

30–90 nm

Starvation, MI

miR-210, miR-132,

CD63, CD9, CD81

Chen et al.34

Precipitation

40–100 nm

H2O2, I/R-injury

(miR-451)

CD63

Xiao et al.39

Precipitation

50–150 nm

H2O2

miR-21

Alix, CD63, CD9

Gray et al.22

UC

96–102 nm

I/R injury

(11 miRNAs)

CD9

  1. EV-purification method (PM), particle size, investigated injury model, main effector mediating protection and EV marker are stated. I/R = ischemia/reperfusion; UC = ultracentrifugation; MI = myocardial infarction; NSI = not specifically indicated; Ref. = reference.
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