Table 3 IC50 of matrine derivatives 1 and 2 against Sf9 cells.
From: Synthesis, characterization and in vitro biological evaluation of two matrine derivatives
Compounds | IC50 (mmol/L) | ||
|---|---|---|---|
24 h | 48 h | 72 h | |
Sophocarpine | 5.59 ± 1.6 | 5.46 ± 0.87 | 5.30 ± 0.59 |
Matrine | 7.68 ± 0.91 | 10.07 ± 3.1 | 6.40 ± 1.8 |
Matrine derivatives 1 | 5.08 ± 0.26 | 0.12 ± 0.03 | 0.07 ± 0.01 |
Matrine derivatives 2 | 4.46 ± 1.4 | 4.07 ± 1.3 | 3.28 ± 0.76 |
