Table 1 Comparison of PLA positive signals among HEK293T cells co-transfected with various combinations of GAD67wt and GAD67mut constructs.

From: A novel homozygous mutation in GAD1 gene described in a schizophrenic patient impairs activity and dimerization of GAD67 enzyme

Mean PLA spots/cell (SD)

ANOVA

Comparison Group

LSD p value

GAD67wt/wt

GAD67wt/mut

GAD67mut/mut

82 (11.3)

78.7 (10.5)

34 (5.7)

F2,6 = 24.094

p = 0.0014

GAD67wt/wt vs GAD67wt/mut

0.681

GAD67wt/wt vs GAD67mut/mut

0.001

GAD67wt/mut vs GAD67mut/mut

0.001