Figure 8 | Scientific Reports

Figure 8

From: Ionic and cellular mechanisms underlying TBX5/PITX2 insufficiency-induced atrial fibrillation: Insights from mathematical models of human atrial cells

Figure 8

Ionic current changes in homozygous TBX5-knockout (Hom-Tbx5), heterozygous TBX5-knockout (Het-Tbx5), homozygous PITX2-knockout (Hom-Pitx2), heterozygous PITX2-knockout (Het-Pitx2), and heterozygous knockout of both PITX2 and TBX5 (Het-Pitx2-Tbx5) atrial cells. Relative transcript expression of TBX5 and PITX2, and relative ionic current of INa, IKs, Ito, IK1, IKur, ICaL, Jup and Jrel in each condition.

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