Figure 2
From: Predicting Tumor Sensitivity to Chemotherapeutic Drugs in Oral Squamous Cell Carcinoma Patients
(A,B) The % apoptotic priming in parental KB and drug-resistant KB CHR 8 5 cells. Cells were exposed to different anticancer drugs at equal concentrations (1 μM) for the different time period. The % apoptotic priming was confirmed by treating the cells with DMSO (positive control) and FCCP (negative control), respectively. It was observed that paclitaxel showed maximum apoptotic priming when compared to the other anticancer drugs (Fig. S6). (C,D) Cytotoxicity of chemotherapeutic drugs (1 µM) on parental KB and drug-resistant KB CHR 8–5 cell lines. Time-dependent curves of chemotherapeutic drugs at fixed concentrations in parental KB and resistant KBCHR 8–5 cell lines. The values shown were the average of experiments each done in triplicate.
