Figure 1

Changes of (A) hindpaw volume, (B) clinical arthritis severity score. Data points represent mean ± SEM. (n = 5–6/group, *p < 0.05, **p < 0.01, ***p < 0.001 vs. initial self control, ##p < 0.01, ###p < 0.001 vs. non-pretreated, two-way repeated measures ANOVA followed by Sidak’s post-test.)