Table 1 Subject Characteristics.

From: Fibroblast gene expression following asthmatic bronchial epithelial cell conditioning correlates with epithelial donor lung function and exacerbation history

 

Asthmatic Subjects

Healthy Subjects

P Value

n = 23

n = 15

Age yrs (mean ± SD)

12.2 (3.0)

11.5 (3.3)

0.5

Sex (% male)

57%

47%

0.6

Currently using inhaled steroids (%)

13 (57%)

  

History of Allergic Rhinitis, n; (%)

19 (83%)

  

History of Eczema, n; (%)

11 (48%)

  

Positive RAST, n; (%)

18 (78%)

  

IgE IU/mL (median ± SD)

273.6 (421.2)

15.3 (11.3)

<0.001

FVC % predicted (mean ± SD)

100.3 (12.9)

104.7 (12.9)

0.2

FEV1% predicted (mean ± SD)

87.7 (13.0)

103.9 (11.9)

0.001

FEV1/FVC Ratio (mean ± SD)

0.79 (0.06)

0.90 (0.1)

<0.001

FEF25–75% predicted (mean ± SD)

68.5 (24.6)

98.0 (20.8)

<0.001

FENO ppb (mean ± SD)

28.1 (35.7)

10.5 (6.2)

0.03

  1. RAST, Radioallergosorbent testing; FVC, Forced vital capacity; FEV1, Forced expiratory volume in one second; FEF25–75, Forced expiratory flow between 25% and 75% of expiration.
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