Table 2 KIR genotype and clinical response.
KIR gene | KIR Present | KIR Absent | Univariate | Multivariate | p-value | Odds ratio (95% CI) |
|---|---|---|---|---|---|---|
Responders/total (rate) | Responders/total (rate) | p-value | Odds ratio (95% CI) | |||
2DL1 | 31/112 (0.28) | 0/0 (NA) | NA | NA | 0.36 | NA |
2DL2 | 6/14 (0.43) | 25/98 (0.26) | 0.23 | 2 (0.62–6.5) | 0.26 | 2.4 (0.71–8.1) |
2DL3 | 31/111 (0.28) | 0/1 (0) | 0.99 | NA | 0.15 | NA |
2DL4 | 31/112 (0.28) | 0/0 (NA) | NA | NA | 0.42 | NA |
2DL5 | 11/41 (0.27) | 20/71 (0.28) | 0.89 | 0.94 (0.39–2.2) | 0.71 | 1.2 (0.46–3) |
2DS1 | 11/39 (0.28) | 20/73 (0.27) | 0.9 | 1.1 (0.43–2.5) | 0.73 | 1.3 (0.5–3.3) |
2DS2 | 7/15 (0.47) | 24/97 (0.25) | 0.11 | 2.5 (0.79–7.6) | 0.15 | 3.1 (0.96–10) |
2DS4 | 31/108 (0.29) | 0/4 (0) | 0.99 | NA | 0.56 | NA |
2DS3 | 5/15 (0.33) | 26/97 (0.27) | 0.55 | 1.4 (0.41–4.6) | 0.38 | 1.7 (0.46–5.6) |
2DS5 | 7/30 (0.23) | 24/82 (0.29) | 0.5 | 0.72 (0.26–1.8) | 0.37 | 0.85 (0.29–2.3) |
2DS3/5 | 11/41 (0.27) | 20/71 (0.28) | 0.89 | 0.94 (0.39–2.2) | 0.71 | 1.2 (0.46–3) |
3DL1 | 31/108 (0.29) | 0/4 (0) | 0.99 | NA | 0.56 | NA |
3DS1 | 10/39 (0.26) | 21/73 (0.29) | 0.75 | 0.86 (0.35–2.1) | 0.89 | 1.1 (0.4–2.7) |
3DL2 | 31/112 (0.28) | 0/0 (NA) | NA | NA | 1 | NA |
3DL3 | 31/112 (0.28) | 0/0 (NA) | NA | NA | 0.99 | NA |
