Table 5 Logistic Regression Analysis of the Risk Factors Associated with the Mechanical Complication and Acute Respiratory Distress Syndrome (ARDS) among Patients with Influenza A(H1N1)pdm09 Virus Infection.
Variables | Mechanical Ventilation | ARDS | ||||||
|---|---|---|---|---|---|---|---|---|
Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | |||||
OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
Gender, male | 1.1 (0.7–2.0) | 0.5 | 1.5 (0.8–2.9) | 0.3 | ||||
6B/6B.1/6B.2 season | 3.4 (2.1–5.6) | <0.001 | 2.6 (1.2–5.6) | 0.02 | 5.0 (2.6–9.96) | <0.001 | 5.5 (1.9–15.9) | 0.002 |
Age group | <0.001 | 0.006 | 0.02 | 0.9 | ||||
≤5 | Reference | Reference | —a | —a | —a | —a | ||
6–18 | 0.7 (0.2–2.4) | 0.6 | 0.8 (0.2–3.4) | 0.76 | —a | —a | —a | —a |
19–49 | 3.7 (1.6–8.6) | 0.002 | 4.0 (1.3–12.6) | 0.02 | Reference | Reference | ||
50–64 | 12.9 (5.4–31) | <0.001 | 3.9 (1.1–13.8) | 0.04 | 2.8 (1.3–5.9) | 0.007 | 0.8 (0.2–2.6) | 0.7 |
≥65 | 27.9 (10.6–73.6) | <0.001 | 9.6 (2.3–39.6) | 0.002 | 2.1 (0.8–5.5) | 0.1 | 0.7 (0.16–2.9) | 0.6 |
Onset to presentation | 1.1 (1.02–1.15) | 0.008 | 1.04 (0.96–1.13) | 0.3 | 1.09 (1.03–1.16) | 0.006 | 1.1 (0.98–1.25) | 0.1 |
Underlying conditions | 14.2 (8.1–24.9) | <0.001 | 5.5 (2.34–13.1) | <0.001 | 10.6 (5.2–21.4) | <0.001 | 2.1 (0.6–6.7) | 0.2 |
Obesity | 7.1 (3.6–14.3) | <0.001 | 2.4 (0.88–6.6) | 0.08 | 11.7 (5.4–25.3) | <0.001 | 3.0 (1.04–8.7) | 0.04 |
Smoking | 10.8 (5.3–22.1) | <0.001 | 2.24 (0.7–7.3) | 0.2 | 16.7 (7.7–36.2) | <0.001 | 2.9 (0.9–9.7) | 0.09 |
Alcoholism | 42.2 (4.9–367) | 0.001 | 8.2 (0.6–109.1) | 0.1 | 32.2 (5.7–181.6) | <0.001 | 3.8 (0.4–39.3) | 0.27 |
Antiviral therapy | <0.001 | 0.03 | <0.001 | 0.05 | ||||
No antiviral therapy | Reference | Reference | Reference | Reference | ||||
Within 48 hours | 8.2 (2.4–27.6) | 0.001 | 3.4 (0.8–14.8) | 0.1 | 12.3 (1.6–94.6) | 0.02 | 5.2 (0.2–124.6) | 0.3 |
After 48 hours | 25.5 (7.8–83.8) | <0.001 | 8.5 (2.1–33.9) | 0.002 | 41.7 (5.6–310.5) | <0.001 | 13.4 (0.7–268.9) | 0.09 |