Table 6 Hazard Ratios for Influenza-related 30-days Mortality and In-hospital Mortality among 453 Hospitalized Patients.

From: Clinical characteristics of patients with laboratory-confirmed influenza A(H1N1)pdm09 during the 2013/2014 and 2015/2016 clade 6B/6B.1/6B.2-predominant outbreaks

Variables

30-day mortality

In-hospital mortality

Univariate analysis

Multivariate analysis

Univariate analysis

Multivariate analysis

Hazard Ratio (95% CI)

P value

Hazard Ratio (95% CI)

P value

Hazard Ratio (95% CI)

P value

Hazard Ratio (95% CI)

P value

Gender, male

3.5 (1.4–8.6)

0.006

3.17 (1.3–7.9)

0.01

2.8 (1.3–5.9)

0.009

2.96 (1.3–6.8)

0.01

6B/6B.1/6B.2 season

1.4 (0.68–2.8)

0.37

  

1.5 (0.8–2.9)

0.2

  

Age group

 

0.002

 

0.14

 

0.003

 

0.2

   ≤5

Reference

 

Reference

 

Reference

 

Reference

 

   6–18

3.1 (0.5–18.6)

0.2

3.4 (0.6–20.2)

0.19

3.2 (0.5–19.2)

0.2

3.5 (0.6–21)

0.17

   19–49

9.4 (1.98–44.8)

0.005

3.6 (0.7–18.3)

0.13

10.4 (2.2–48.1)

0.003

4.7 (0.96–22.8)

0.06

   50–64

6.8 (1.4–34.1)

0.02

2.09 (0.4–11.1)

0.4

7.7 (1.6–37.2)

0.01

2.7 (0.5–14.2)

0.2

   ≥65

18.1 (3.9–84.5)

<0.001

5.6 (1.1–27.7)

0.04

16.6 (3.5–77.6)

<0.001

5.5 (1.1–27.3)

0.04

Onset to presentation

0.99 (0.9–1.1)

0.79

  

0.98 (0.9–1.1)

0.7

  

Underlying conditions

10.3 (3.5–30.5)

<0.001

7.2 (2.2–23.7)

0.001

8.5 (3.2–22.7)

<0.001

6.9 (2.4–20.2)

<0.001

Obesity

1.0 (0.36–2.8)

1

  

0.8 (0.3–2.04)

0.6

  

Smoking

1.7 (0.74–3.9)

0.2

  

1.9 (0.9–4.1)

0.09

0.7 (0.3–1.7)

0.5

Alcoholism

4.5 (1.3–15.6)

0.02

2.7 (0.74–10.1)

0.13

4.5 (1.3–15.6)

0.02

2.8 (0.7–10.4)

0.1

Antiviral therapy

—a

—a

—a

—a

—a

—a

—a

—a

  1. aData cannot be calculated because none of the patients who did not receive antiviral therapy died.
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