Figure 2 | Scientific Reports

Figure 2

From: Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs

Figure 2

VMAT2 availability determined by in vivo [11C]-DTBZ PET. (a) [11C]-DTBZ BPND values calculated using Logan reference tissue model in striatum, ventral midbrain and anterior pons in 6 minipigs. Values are shown for naïve minipigs and for minipigs inserted with the injection port following a few saline injections (baseline), and after a cumulative dose of 200 and 400 μg lactacystin. **< 0.01 (b) BPND parametric maps are shown for a representative minipig at baseline, 200 and 400 μg in coronal view at the level of striatum, ventral midbrain and anterior pons.

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