Table 1 Radiotracer information.

From: Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs

 

[11C]-DTBZ

[11C]-yohimbine

[11C]-DASB

[11C]-PK11195

ID

IM

N

ID

IM

N

ID

IM

N

ID

IM

N

Naïve

387 ± 14

2.1 ± 1.9

6

         

Saline

364 ± 40

2.5 ± 3.6

6

378 ± 28

2.7 ± 5.5

6

401 ± 40

2.9 ± 4.0

5

371 ± 10

1.8 ± 0.8

3

200 μg

387 ± 34

0.6 ± 0.4

6

381 ± 34

1.4 ± 0.9

6

331 ± 47

3.4 ± 4.1

5

311 ± 125

2.6 ± 3.9

3

400 μg

384 ± 48

3.2 ± 3.1

6

375 ± 32

1.9 ± 1.4

6

344 ± 39

2.3 ± 2.4

4

   
  1. Average ± standard deviation of injected dose (ID, MBq) and injected mass (IM, μg) for each tracer. N is the sample size for each tracer at baseline and 200 and 400 μg doses of lactacystin.
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