Figure 5 | Scientific Reports

Figure 5

From: Ptf1a inactivation in adult pancreatic acinar cells causes apoptosis through activation of the endoplasmic reticulum stress pathway

Figure 5

Splicing of Xbp1 mRNA was suppressed in Ptf1a cKO mice on day 3 but recovered by day 10. (a) Representative electrophoresis of RT-PCR products of unspliced and spliced Xbp1 mRNA on day 3. (b) Comparison of the percentage of spliced Xbp1 mRNA on day 3 in control and Ptf1a cKO mice. control, n = 5; Ptf1a cKO, n = 6. (c) Representative electrophoresis of RT-PCR products of unspliced and spliced Xbp1 mRNA on day 10. (d) Comparison of the percentage of spliced Xbp1 mRNA on day 10 in control and Ptf1a cKO mice. control, n = 6; Ptf1a cKO, n = 5. *P < 0.05. The original, unprocessed scans of the gels are shown in Supplementary Fig. S6.

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