Figure 6

WNT7A promoted the EMT process via activating WNT/β-catenin pathway. (A) Gene set enrichment analysis plot based on the gene expression profiles of TCGA samples grouped by expression of WNT7A. (B) The expression of β-catenin, E-cadherin and N-cadherin in PDAC cell lines with WNT7A down-regulated and over-expressed are detected by Western blot. The relative expression was normalized to β-actin in cell lines.