Table 3 Diagnostic efficacy parameters for panel of combined autoantibody biomarkers (PGAM1, CMYC, MUC1, TPI, and MNSOD).
From: Multiplexed Autoantibody Signature for Serological Detection of Canine Mammary Tumours
ROC analysis for combined biomarker panel | ||
|---|---|---|
Statistics | Value | 95% CI |
Sensitivity | 78.6% | 66.21% to 86.21% |
Specificity | 90% | 80.77% to 97.78% |
AUC | 0.931 | 0.870 to 0.968 |
z statistic | 20.86 | — |
Youden index J | 0.70 | — |
Positive Likelihood Ratio | 4.83 | 2.53 to 9.23 |
Negative Likelihood Ratio | 0.27 | 0.17 to 0.42 |
Positive Predictive Value | 87.88% | 79.15% to 93.26% |
Negative Predictive Value | 71.19% | 61.52% to 79.24 |
