Figure 4

Time course of the brain average Ultrafast Doppler signal in the 2 groups, compared with the time course of the mean arterial blood pressure (MAP). (a) UfD level (proportional to the blood volume) in Total Liquid Ventilation (TLV) group (blue) compared to Control group (red) over the course of the experiment (baseline, asphyxia, CPR and monitoring post resuscitation). Solid line: average value on N = 5 individuals, overlay: corrected sample standard deviation. (b) Mean arterial blood pressure for both groups during the course of the experiment. Solid line: average value, light color: corrected sample standard deviation. (c) Area under the curve of UfD signals for both groups between t = 7 minutes and t = 37 minutes. Hyperemia was significantly higher in the control group than in the TLV group (p < 0.05, Mann Whitney U test). Box plots show the median and interquartile and extreme AUC values per group. (d) Average arterial blood pressure during the same time period (t = 7 minutes to t = 37 minutes). The MAP was also significantly different between the two groups (p < 0.05, Mann Whitney U test) with a slightly lower tendency for the TLV group, with average values in the physiological range.