Table 2 Differentially regulated miRNAs in the villus-crypt axis have genomic targets among the putative proteins in which the expression profile was affected by CD98 overexpression.

From: Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis

Putative targets

miRNAs targeting the putative target gene

# of miRNAs

Single Target

Multiple Targets

Prss1

 

miR-17-3p

1

Gpi1

 

miR-425-5p, miR-150-5p

2

Eef2

miR-322-5p, miR-497-5p

miR-709, miR-326-3p, miR-484

5

Actb

miR-132-3p, miR-1a-3p

miR-18a-5p, miR-802-5p

4

Mttp

 

miR-30a-5p, miR-30e-5p

2

Cps1

miR-151-5p

 

1

Krt78

miR-31-5p, miR-134-5p

miR-199a-5p

3

Tfrc

miR-7a-5p, miR-221-3p, miR-365-3p, miR-7b-5p

miR-30a-5p, miR-30e-5p, miR-130b-5p

7

Ezr

 

miR-17-3p

1

Hspa5

miR-374b-5p, miR-350-3p

miR-130b-3p, miR-301a-3p, miR-351-5p, miR-130a-3p, miR-148a-3p, miR-152-3p, miR-125a-5p, miR-125b-5p, miR-150-5p, miR-351-5p

12

Immt

miR-191-3p

miR-342-3p, miR-802-5p, miR-203-5p

4

Dlat

miR-191-5p, miR-194-5p, miR-872-3p

miR-421-3p

4

Atic

miR-30e-3p, miR-455-3p

miR-18a-5p, miR-342-3p, miR-709, miR-326-3p

6

Me2

miR-106a-5p, miR-17-5p, miR-93-5p

miR-351-5p, miR-101a-3p, miR-144-3p, miR-125a-5p, miR-125b-5p, miR-203-5p

9

Cct6a

miR-26a-5p, miR-26b-5p

miR-101a-3p, miR-144-3p, miR-7a-1-3p, miR-130b-5p

6

Canx

 

miR-130b-3p, miR-301a-3p, miR-130a-3p, miR-144-3p, miR-148a-3p

5

P4hb

 

miR-199a-5p, miR-484

2

Pkm

miR-378a-5p

miR-130b-5p

2

Atp5b

 

miR-23a-3p

1

Fkbp4

miR-21a-3p, miR-137-3p

miR-181a-5p, miR-181d-5p

4

Pm20d1

 

miR-143-3p, miR-674-3p

2

Cndp2

 

miR-351-5p, miR-709, miR-125a-5p, miR-125b-5p, miR-351-5p, miR-674-3p

6

Krt2

 

miR-23a-3p

1

Calr

miR-22-5p

miR-709, miR-148a-3p, miR-152-3p, miR-143-3p

5

Pdia6

miR-106b-5p, miR-20a-5p

miR-181a-5p, miR-181d-5p, miR-23a-3p

5

Capza1

 

miR-181a-5p, miR-181d-5p, miR-23a-3p, miR-30a-5p, miR-30e-5p, miR-7a-1-3p

6

Taldo1

miR-19b-3p

miR-130b-3p, miR-301a-3p, miR-130a-3p

4

Rpsa

 

miR-425-5p

1

Mlec

miR-399-5p

miR-421-3p, miR-674-3p

3

Total

29

32

31

  1. miRNAs listed in each row represents miRNAs targeting the putative target gene listed in the corresponding row. miRNAs listed under “Single Target” refer to miRNAs that solely target the gene in the same row, whereas the miRNAs listed under “Multiple Targets” refer to miRNAs targeting genes listed elsewhere in the table, including the one it is listed under. Values in very far right panel refer to the number of miRNAs targeting the putative gene in the corresponding row.
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